Well...kind of in the same way as the question on cystic fibrosis at the end of chapter 12. First, you want to find out how many "morphs" ("alleles") there are for the RFLP. Then, find out if the condition is dominant or recessive. Then, see if everyone who has the syndrome also has a certain restriction fragment. Note that each person's RFLP pattern is indicated below the pedigree symbol for that person (e.g. the second lane from the left corresponds to the affected female in generation I).
You'll find a "morph" for the RFLPs that, when it comes from a certain parent, always goes with the condition. Now look at the girl in generation III....
(By the way, everyone: I very strongly recommend eviewing pedigrees with molecular markers. They are important!)
3 Comments:
I HATE THIS FCD QUESTION. HOW THE HELL DO YOU DO IT?
Well...kind of in the same way as the question on cystic fibrosis at the end of chapter 12.
First, you want to find out how many "morphs" ("alleles") there are for the RFLP.
Then, find out if the condition is dominant or recessive.
Then, see if everyone who has the syndrome also has a certain restriction fragment.
Note that each person's RFLP pattern is indicated below the pedigree symbol for that person (e.g. the second lane from the left corresponds to the affected female in generation I).
You'll find a "morph" for the RFLPs that, when it comes from a certain parent, always goes with the condition. Now look at the girl in generation III....
(By the way, everyone: I very strongly recommend eviewing pedigrees with molecular markers. They are important!)
Cheers
Pam
I understand your frustration but no need to be so grumpy :)
Anonymous said...I HATE THIS FCD QUESTION. HOW THE HELL DO YOU DO IT?
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